As you age, especially during important transitions like perimenopause and menopause, your skin goes through some pretty major changes. Dryness, thinning, and wrinkles aren't just common; they're expected. It's not just about your appearance, though. The way your skin ages can contribute to how the rest of your body ages. (1)
Your skin is your largest organ, acting as a barrier between you and the environment. So when it starts to show signs of aging, those changes are often reflected in deeper shifts happening in the rest of your body. That's why it's so important to take proactive steps in caring for your skin, especially as you age.
The Role of the Skin Barrier in Aging
Your skin barrier, a thin layer of skin cells and lipids, acts as a defense against harmful factors like UV rays and environmental pollutants that can create inflammation. But when this barrier becomes damaged, which often happens to aging skin, it's less able to defend itself against these threats.
For women going through perimenopause and menopause, a weakened barrier can trigger the persistent release of inflammatory chemicals into the skin and bloodstream. When this low-level inflammation becomes chronic, it can potentially speed up the aging process and worsen common age-related conditions like heart disease and dementia. (2)
That's what led the team of researchers at OneSkin to explore the effects of their OS-01 BODY moisturizer on whole-body aging. After seeing the success of their OS-01 Peptide™ in their flagship product, OS-01 FACE, they wanted to see what it could do for systemic health when used across the vast majority of skin on the body. (3, 4)
In their recently published clinical study (which I highly recommend reading here), OS-01 BODY specifically improved skin functions that help combat signs of skin aging. Not only did OS-01 BODY give their participants a massive boost in skin hydration, but it also improved their skin barrier function by up to +41.49%. (1)
Thanks to that considerable improvement in skin barrier function, the participants of the study saw a significant decrease in the levels of a key biomarker of inflammation in their blood, IL-8. (1) These results were fascinating and highlight the huge role that skin health plays in your overall health and longevity.
What Do These Improvements Actually Mean for Your Skin?
Due to the impressive improvements in hydration and barrier function, OS-01 BODY works wonders for the visible appearance and feel of your skin. Now, I know what you're thinking. Every skin care company promises that their products will drastically change how your skin looks and feels. But when I took a look at some of the before-and-afters on their site, my jaw dropped.
As it turns out, targeting the cellular changes responsible for skin aging is a must-have for anyone wanting to visibly improve the appearance, feel, and longevity of their skin.
Want to try it for yourself? Visit oneskin.co and use code DRSTEPHANIE to save 15% off your first purchase.
References:
01 Zonari, A., et al. Journal of Cosmetic Dermatology, 2025
02 https://pmc.ncbi.nlm.nih.gov/articles/PMC6146930/
03 Zonari, A., et al. Journal of Cosmetic Dermatology, 2024
04 Based on data from clinical studies, consumer perception studies, and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims