episode #341

Mitochondria, Muscle Mass, and Urolithin A with Dr. Anurag Singh


Dr. Anurag Singh, an expert in urolithin A research, joins Dr. Stephanie to shed light on the potential health benefits of Urolithin A. This compound, found in foods such as pomegranate, raspberries, pecans, and walnuts, has been linked to improved muscle function, cardiovascular health, brain cognition, skincare, and more by boosting mitochondrial function.

Learn where Urolithin A is produced in the body, who benefits from it, and its impact on various aspects of life, from the immune system to brain health. Discover the science behind this innovative compound and the dedication to research and development that sets it apart from traditional supplements. Don’t miss this eye-opening conversation with a true game-changer in the field of aging and wellness.

Dr. Singh also delves into his research findings on how urolithin A influences overall health and disease prevention, and the importance of incorporating it into our diets. In this episode, you will learn about the science and research behind Urolithin A and how it’s revolutionizing the way we approach aging. Tune in and discover the key to a healthier, more vibrant life with this fascinating discussion.


Anurag Singh is currently Chief Medical Officer at Timeline, developing next-generation advanced nutritional and skincare products targeting improvements in mitochondrial and cellular health. With an M.D. in internal medicine and a Ph.D. in immunology, his experience includes work at top consumer health (Nestlé, Nestlé Health Science) and startup companies (Amazentis/Timeline). He’s authored > 40 articles for top science journals, been awarded >15 patents, and designed and led > 50 randomized clinical trials. His research over the past decade across multiple clinical trials on the postbiotic Urolithin A and its health benefits has led to the launch of multiple consumer products.


Impact of the Natural Compound Urolithin A on Health, Disease, and Aging




0:00:00 The Connection Between Mitochondria and Immune Health
0:01:18 Introduction to the Game-Changing Compound: Urolithin A
0:04:34 Introduction to Dr. Anurag Singh and Urolithin A
0:07:22 Urolithin A as a Postbiotic and Its Impact on Health
0:10:11 Gut Microbiome Diversity and Richness in Urolithin A Production
0:12:41 Possibility of Changing the Environment to Enhance Urolithin A Production
0:15:28 Urolithin A’s Influence on Skeletal Muscle and Mitophagy
0:18:04 Measuring Improvement in Mitophagy with Urolithin A
0:21:08 Urolithin A’s Impact on Metabolic Function and Lipid Markers
0:26:31 Urolithin A Supplementation Improves Skeletal Muscle Strength and Endurance
0:31:13 Improved Recovery for Amateur Athletes
0:34:16 Urolithin A as a Post-Workout Supplement
0:36:53 Urolithin A’s Effects on Mitophagy for Disc and Joint Health
0:39:43 Joint and Muscle Health: Mitophagy and Inflammation
0:42:56 Reduction in Redness and Photo Damage
0:52:13 Safety Evaluation and FDA Approval of the Molecule
0:55:14 Therapeutic Intervention and Environmental Considerations



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I’m Dr. Stephanie

Part geek, part magic, and all the way passionate about being a well-lived woman.

I want to throw my grandkids in the air in my 70’s. I want to be squatting even more weight than I am now, and putting my OWN luggage in the overhead bin. Sound like weird goals? For me these are just some of the little things that represent a life well-lived.

My health is MY job – I’ll be damned if I rely on luck, ‘good genes’ or a cocktail of drugs that over promise and under deliver.

The Betty Body is my first book-baby, and a collection of what I’ve learned after thousands of clinical hours, hundreds of conversations with the world’s top experts, and most importantly…

This book is an outline of what took ME from “rock-bottom health” at 38, to being my own version of a Betty in my perimenopausal mid 40’s. A woman who is physically strong, full of energy, enjoys mental clarity, great sex and a joyful family life. Is it all roses? Of course not. But I have the stamina and tools to deal with the push and pull of life so that it doesn’t turn into chronic stress.

I want this for you too. Let’s go Bettys!