Metabolic Effects of Uric Acid, Fructose, and Salt with Dr. David Perlmutter

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Metabolic Effects of Uric Acid, Fructose, and Salt with Dr. David Perlmutter

Dr. Stephanie and Dr. David Perlmutter, a board-certified neurologist and 5X NYT best-selling author discuss the new understanding of Uric Acid in the context of gout, arthritis, purines, the way that we get gout through the consumption of sugar and fructose in particular. Dr. Perlmutter reveals the metabolism of fructose and why it’s so insanely addictive. We go over the evolutionary selective bias and the reason why we burn fat vs storing fat. You’ll understand the Sodium Paradox, Serum Osmolality, and their relation to Uric Acid. Of course, we’ll discuss how the ketogenic diet affects your levels of Uric Acid and how keto cycling can help. You’ll get our proven dietary and lifestyle hacks to lower uric acid, find out the ideal Uric Acid range you should fit within, and how specific medications and alcohol are affecting your body.

Episode Overview:  

  • 1:15 Introduction
  • 4:55 Welcoming David
  • 6:19 New Understanding Uric Acid
  • 10:00 Purines and Fructose
  • 16:00 Metabolism Of Fructose And Why It’s Addicting
  • 24:25 Evolutionary Selective Bias
  • 37:04 The Reason Why We Burn Fat Vs. Storing Fat
  • 43:44 The Sodium Paradox, Serum Osmolality And Uric Acid
  • 58:14 Ketogenic Diet and Uric Acid
  • 1:01:16 Keto Cycling
  • 1:05:52 Dietary and Lifestyle Interventions To Lower Uric Acid
  • 1:15:34 Alcohol and Obesity
  • 1:19:10 Medication That Increases Uric Acid
  • 1:22:00 The Ideal Uric Acid Range
  • 1:26:00 Conclusion

I’m Dr. Stephanie

Part geek, part magic, and all the way passionate about being a well-lived woman.

I want to throw my grandkids in the air in my 70’s. I want to be squatting even more weight than I am now, and putting my OWN luggage in the overhead bin. Sound like weird goals? For me these are just some of the little things that represent a life well-lived.

My health is MY job – I’ll be damned if I rely on luck, ‘good genes’ or a cocktail of drugs that over promise and under deliver.

The Betty Body is my first book-baby, and a collection of what I’ve learned after thousands of clinical hours, hundreds of conversations with the world’s top experts, and most importantly…

This book is an outline of what took ME from “rock-bottom health” at 38, to being my own version of a Betty in my perimenopausal mid 40’s. A woman who is physically strong, full of energy, enjoys mental clarity, great sex and a joyful family life. Is it all roses? Of course not. But I have the stamina and tools to deal with the push and pull of life so that it doesn’t turn into chronic stress.

I want this for you too. Let’s go Bettys!