episode #343

Fat Accumulation & Female Metabolism with Dr. Benjamin Bikman


In this special rebroadcast, Dr. Benjamin Bikman, the renowned metabolic research scientist is back. And in this episode, he and Dr. Stephanie dive into the complexities of insulin resistance and sensitivity during the menstrual cycle, and also discuss the importance of protein and the best types to include in your diet.

Dr. Bikman is an expert in the intricate topic of fat metabolism, specifically exploring how fat cells transform from reproductive to menopausal years and the metabolic implications of this transition. This conversation also covers insulin resistance and sensitivity throughout the menstrual cycle, addressing female-specific disorders, optimal protein sources, and the nuanced mechanisms of different types of fat.

With a deliberate focus on empowering women to embrace a positive perspective on fat, the episode provides valuable insights for those in both reproductive and menopausal stages, offering a deep dive into the metabolic consequences faced by women in these phases of life.

This lively and informative chat with Dr. Bikman with leave you with a brand-new perspective on fat.


Dr. Bikman’s research focus is to elucidate the molecular mechanisms that mediate the disruption that causes and accompanies metabolic disorders, such as obesity, type 2 diabetes, and dementia. Driven by his academic training (Ph.D. in Bioenergetics and postdoctoral fellowship with the Duke-National University of Singapore in metabolic disorders), he is currently exploring the contrasting roles of insulin and ketones as key drivers of metabolic function. He frequently publishes his research in peer-reviewed journals and presents at international science meetings.


The previous episode with Ben: Ben Bikman on Why We Get Sick, Insulin Resistance and Infertility

Ben Bikman glucagon talk: https://www.youtube.com/watch?v=z3fO5aTD6JU&ab_channel=LowCarbDownUnder

Survival of the Fattest book: https://amzn.to/3uAIuug

HLTH CODE meal replacement shake: https://gethlth.com/


Website – https://www.insuliniq.com


0:00 – Intro
0:05:11 The Importance of Fat Cells and Their Role in Metabolism
0:11:11 Mitochondria in Brown Fat Cells and Cellular Work
0:14:32 The Beiging Effect on White Fat Cells
0:20:05 Society’s Issue: Offense in Scientific Discussions
0:24:12 Sex Hormones and Fat Storage in Females
0:28:31 The Metabolic Burden of Pregnancy and Lactation
0:37:13 Women’s Metabolic Changes with Age and Fertility
0:46:50 The Effects of Hypertrophic Fat Cells
0:50:40 Glucagon: The Opposite of Insulin
0:56:06 Protein and Glucose Interaction and Insulin Spiking Effect
1:05:36 The Challenges of Plant Proteins and Heavy Metals
1:09:00 The Controversial Role of Protein in the Blue Zones
1:18:42 Resistance Training for Muscle Growth
1:28:08 Convenient Nutrition for Busy Lifestyles
1:29:41 The Importance of Ending a Fast Properly



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I’m Dr. Stephanie

Part geek, part magic, and all the way passionate about being a well-lived woman.

I want to throw my grandkids in the air in my 70’s. I want to be squatting even more weight than I am now, and putting my OWN luggage in the overhead bin. Sound like weird goals? For me these are just some of the little things that represent a life well-lived.

My health is MY job – I’ll be damned if I rely on luck, ‘good genes’ or a cocktail of drugs that over promise and under deliver.

The Betty Body is my first book-baby, and a collection of what I’ve learned after thousands of clinical hours, hundreds of conversations with the world’s top experts, and most importantly…

This book is an outline of what took ME from “rock-bottom health” at 38, to being my own version of a Betty in my perimenopausal mid 40’s. A woman who is physically strong, full of energy, enjoys mental clarity, great sex and a joyful family life. Is it all roses? Of course not. But I have the stamina and tools to deal with the push and pull of life so that it doesn’t turn into chronic stress.

I want this for you too. Let’s go Bettys!